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Whole body diffusion for metastatic disease assessment in neuroendocrine carcinomas: comparison with OctreoScan® in two cases.

Identifieur interne : 000934 ( Main/Exploration ); précédent : 000933; suivant : 000935

Whole body diffusion for metastatic disease assessment in neuroendocrine carcinomas: comparison with OctreoScan® in two cases.

Auteurs : RBID : pubmed:22591909

English descriptors

Abstract

Neuroendocrine tumor (NET) patients must be adequately staged in order to improve a multidisciplinary approach and optimal management for metastatic disease. Currently available imaging studies include somatostatin receptor scintigraphy, like OctreoScan®, computed tomography (CT), scans and magnetic resonance imaging (MRI), which analyze vascular concentration and intravenous contrast enhancement for anatomic tumor localization. However, these techniques require high degree of expertise for interpretation and are limited by their availability, cost, reproducibility, and follow-up imaging comparisons. NETs significantly reduce water diffusion as compared to normal tissue. Diffusion-weighted imaging (DWI) in MRI has an advantageous contrast difference: the tumor is represented with high signal over a black normal surrounding background. The whole-body diffusion (WBD) technique has been suggested to be a useful test for detecting metastasis from various anatomic sites. In this article we report the use of DWI in MRI and WBD in two cases of metastatic pulmonary NET staging in comparison with OctreoScan® in order to illustrate the potential advantage of DWI and WBD in staging NETs.

DOI: 10.1186/1477-7819-10-82
PubMed: 22591909

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Le document en format XML

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<title xml:lang="en">Whole body diffusion for metastatic disease assessment in neuroendocrine carcinomas: comparison with OctreoScan® in two cases.</title>
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<name sortKey="Cossetti, Rachel Jorge D" uniqKey="Cossetti R">Rachel Jorge D Cossetti</name>
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<name sortKey="Bezerra, Regis Otaviano Franca" uniqKey="Bezerra R">Regis Otaviano França Bezerra</name>
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<name sortKey="Gumz, Brenda" uniqKey="Gumz B">Brenda Gumz</name>
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<name sortKey="Telles, Adriana" uniqKey="Telles A">Adriana Telles</name>
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<name sortKey="Costa, Frederico P" uniqKey="Costa F">Frederico P Costa</name>
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<div type="abstract" xml:lang="en">Neuroendocrine tumor (NET) patients must be adequately staged in order to improve a multidisciplinary approach and optimal management for metastatic disease. Currently available imaging studies include somatostatin receptor scintigraphy, like OctreoScan®, computed tomography (CT), scans and magnetic resonance imaging (MRI), which analyze vascular concentration and intravenous contrast enhancement for anatomic tumor localization. However, these techniques require high degree of expertise for interpretation and are limited by their availability, cost, reproducibility, and follow-up imaging comparisons. NETs significantly reduce water diffusion as compared to normal tissue. Diffusion-weighted imaging (DWI) in MRI has an advantageous contrast difference: the tumor is represented with high signal over a black normal surrounding background. The whole-body diffusion (WBD) technique has been suggested to be a useful test for detecting metastasis from various anatomic sites. In this article we report the use of DWI in MRI and WBD in two cases of metastatic pulmonary NET staging in comparison with OctreoScan® in order to illustrate the potential advantage of DWI and WBD in staging NETs.</div>
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<RefSource>AJR Am J Roentgenol. 2008 Jan;190(1):67-73</RefSource>
<PMID Version="1">18094295</PMID>
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<RefSource>Ann Oncol. 2005 Nov;16(11):1806-10</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>Abdom Imaging. 1999 Sep-Oct;24(5):456-61</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>Surgery. 1990 Dec;108(6):1091-6</RefSource>
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<CommentsCorrections RefType="Cites">
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<CommentsCorrections RefType="Cites">
<RefSource>Eur Radiol. 2008 Mar;18(3):486-92</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>J Am Coll Surg. 2000 Apr;190(4):432-45</RefSource>
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<RefSource>Br J Radiol. 2001 Nov;74(887):1065-70</RefSource>
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<CommentsCorrections RefType="Cites">
<RefSource>Eur J Radiol. 2010 Sep;75(3):376-83</RefSource>
<PMID Version="1">19497694</PMID>
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<RefSource>J Nucl Med. 2010 May;51(5):669-73</RefSource>
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<RefSource>J Nucl Med. 2010 Mar;51(3):353-9</RefSource>
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<RefSource>J Clin Oncol. 2008 Jun 20;26(18):3063-72</RefSource>
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